| Diners Club International | Riverwoods | 1950 |
| DirecTV | El Segundo | 1990 |
| DisneyToon Studios | Glendale | 1 de abril de 1990 |
| Dolby Laboratories | São Francisco | 1965 |
| Doubleday | Nova Iorque, Garden City (Nova Iorque) | 1897 |
| DoubleTree by Hilton | McLean | 1969 |
| Dow Inc. | Midland | 1 de janeiro de 2019 |
| Dun & Bradstreet | — | 1841 |
| Dunkin' Brands | Canton | 1950 |
| Dunlop Manufacturing | Benicia | 1965 |
| EarthLink | Atlanta, Pasadena, Atwater Village | 1994 |
| Eastman Chemical Company | Kingsport | 1920 |
| Eastman Kodak | Rochester, Nova Iorque | 1882 |
| EBay | São José | 3 de setembro de 1995 |
| EMachines | Irvine | setembro 1998 |
| Energy Transfer | Dallas | 1996 |
| Ensoniq | Malvern | 1982 |
| EPAM Systems | Newtown, Pensilvânia | 1993 |
| Exelon | Chicago | 2000 |
| Expedia | Seattle | 22 de outubro de 1996 |
| Expeditors International | Seattle | 1979 |
| ExxonMobil | Spring | 5 de agosto de 1882 |
| FEI Company | Hillsboro | 1971 |
| Fenway Sports Group | Boston | 2001 |
| Fidelity Investments | Boston | 1946 |
| Fiserv | Brookfield | 1984 |
| Flex LTD | São José, Singapura | 1969 |
| Fluke Corporation | Everett | 1948 |
| Food Lion | Salisbury | 1957 |
| Foot Locker | Nova Iorque | 1974 |
| Framework | Burlingame | dezembro 2019 |
| Freeport-McMoRan | Phoenix | 1912 |
| Gannett Company | Tysons Corner, Nova Iorque | 6 de outubro de 1906 |
| Gap | São Francisco | 1969 |
| Gateway | Irvine | 1 de setembro de 1985 |
| Genuity | Frankfurt am Main | 1985 |
| Genzyme | Cambridge | 1981 |
| Gilead Sciences | Foster City | junho 1987 |
| GlobalFoundries | Malta | 7 de outubro de 2008 |
| Glu Mobile | São Francisco | 2005 |
| GMT Games | Hanford | 1990 |
| GoFundMe | — | 2010 |
| Golden Boy Promotions | Los Angeles | 2002 |
| Goodrich Corporation | Charlotte | 1870 |
| Goodyear | Akron | 29 de agosto de 1898 |
| Groq | Mountain View | 2016 |
| Grubhub | Chicago | 2004 |
| Hasbro | Pawtucket | 1923 |